Manual Colloids in Drug Delivery (Surfactant Science)

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Chapter 6 Micelles. Chapter 7 Multiple Emulsions. Chapter 17 Liposomes and Biomacromolecules. Chapter 19 Dendrimers in Drug Delivery. Chapter 20 Microsphere. Chapter 9 Nanoemulsions as Drug Delivery Systems. Chapter 10 Microemulsion Systems.

Dendrimer–surfactant interactions - Soft Matter (RSC Publishing)

Chapter 25 Nanocarriers for Imaging Applications. Hak Cipta. Informasi bibliografi. Colloids in Drug Delivery Monzer Fanun CRC Press , 19 Apr - halaman 1 Resensi Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Back cover. Cogent Medicine. Pharmaceutical Science.

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Authors Close Fakhar ud Din fudin qau. Sehrish Saleem sehrish. Fatima Aleem fatimaaleem gmail. Rida Ahmed rida. Noor ul Huda its. Sohail Ahmed sohailahmed gmail. Nadra Khaleeq nadrakhaleeq gmail. Kifayat Ullah Shah fudin qau. Alam Zeb alam.

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Article Figures and tables References. Abstract Abstract Bioavailability of the colloidal particles is of great concern. Introduction Bioavailability is the unchanged fraction of a drug in the blood circulation, which is available for its therapeutic use. Particle technologies Particle technology is a bunch of techniques, used to enhance physicochemical, micrometrics and biopharmaceutical characteristics of the hydrophobic drugs, resulting in their improved solubility and bioavailability. Freeze-dried liposomes Liposomes are the phospholipid vesicles, comprising entirely of a phospholipid bilayer which surrounds an aqueous compartment within its hydrophilic head and thus can dissolve both lipophilic and hydrophilic drugs.

PMs PMs are nanosized formulations which have the capacity to carry water insoluble drugs to their targeted areas for their intended pharmacological effects. Formulation-based approaches Out of all newly discovered compound known in medication disclosure projects, compounds are inadequately soluble in water Allam, El. Co-crystallization Co-crystals mainly comprise two parts; the API and the former. Cosolvency The solubility of a poorly water-soluble drug is improved normally by adding a water-soluble solvent, these solvents are called cosolvents Strickley, Hydrotrophy Hydrotrophy was introduced by Carl neuberg in , however, practically it was implicated by thoma and colleagues in Sekhon, Conclusion Bioavailability in a specific range is required for all therapeutic agents in order to achieve their intended effects.

Current Opinion in Colloid & Interface Science

Funding This research did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors. References Adams, M. Amphiphilic block copolymers for drug delivery. Journal of Pharmaceutical Sciences , 92 7 , — Powdered self-emulsified lipid formulations of meloxicam as solid dosage forms for oral administration.

Drug Development and Industrial Pharmacy , 39 11 , — International Journal of Nanomedicine , 11, — Gamal, S.

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Bioavailability: A pharmaceutical review. Effects of cyclodextrin derivatives on bioavailability of Ketoprofen. Drug Development and Industrial Pharmacy , 23 4 , — International Research Journal of Pharmacy , 3 5 , The solubility of benzodiazepines in sodium salicylate solution and a proposed mechanism for hydrotropic solubilization. International Journal of Pharmaceutics , 13 1 , 67— Pharma Ventures Ltd, 1, Spray-freeze-dried dry powder inhalation of insulin-loaded liposomes for enhanced pulmonary delivery.

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Journal of Drug Targeting , 16 9 , — Melt extrusion: From process to drug delivery technology. European Journal of Pharmaceutics and Biopharmaceutics , 54 2 , — Preparation and reactivity of nanocrystalline cocrystals formed via sonocrystallization. Journal of the American Chemical Society , 1 , 32— Macromolecules , 27 5 , Dendrimer-mediated transdermal delivery: Enhanced bioavailability of indomethacin.

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Journal of Controlled Release , 90 3 , — Preparation and evaluation of glibenclamide-polyglycolized glycerides solid dispersions with silicon dioxide by spray drying technique. European Journal of Pharmaceutical Sciences , 26 2 , — Nanonization strategies for poorly water-soluble drugs. Drug Discovery Today , 16 7 , — Development of a solid supersaturatable self-emulsifying drug delivery system of docetaxel with improved dissolution and bioavailability.

Biological and Pharmaceutical Bulletin , 34 2 , To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. Journal of Control Release , 2 , — Formulation design, preparation and physicochemical characterizations of solid lipid nanoparticles containing a hydrophobic drug: Effects of process variables.

Colloids and Surfaces B: Biointerfaces , 88 1 , — Cyclodextrins and their uses: A review. Process Biochemistry , 39 9 , — Drug delivery strategies for poorly water-soluble drugs. Expert Opinion on Drug Delivery , 4 4 , — Cyclodextrins in pharmacy. Dordrecht: Kluwer Academic Publishers.

Drug nanocrystals for the formulation of poorly soluble drugs and its application as a potential drug delivery system. Journal of Nanoparticle Research , 10 5 , — Block copolymer micelles: Preparation, characterization and application in drug delivery. Journal of Controlled Release , 1 , — Advanced Pharmaceutical Bulletin , 3 1 , Journal of Pharmaceutical Sciences , 92 8 , — Polymeric Micelles: Recent advancements in the delivery of anticancer drugs.

Pharmaceutical Research , 33 1 , 18— The textbook of pharmaceutical medicine. Bioavailability of seocalcitol. European Journal of Pharmaceutical Sciences , 28 3 , — Formulation strategies to improve the bioavailability of poorly absorbed drugs with special emphasis on self-emulsifying systems. ISRN Pharmaceutics , Nanoparticle engineering processes for enhancing the dissolution rates of poorly water soluble drugs. Drug Development and Industrial Pharmacy , 30 3 , — Application of dendrimer—drug complexation in the enhancement of drug solubility and bioavailability.

Polymeric micelles — a new generation of colloidal drug carriers. European Journal of Pharmaceutics and Biopharmaceutics , 48 2 , — Exploring solid lipid nanoparticles to enhance the oral bioavailability of curcumin. Journal of Microencapsulation , 31 3 , — Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: Basic approaches and practical applications.

International Journal of Pharmaceutics , 1 , 1— Modification of physicochemical characteristics of active pharmaceutical ingredients and application of supersaturatable dosage forms for improving bioavailability of poorly absorbed drugs. Advanced Drug Delivery Reviews , 64 6 , — Enhanced oral bioavailability of doxorubicin in a dendrimer drug delivery system.

Current Opinion in Colloid & Interface Science

Journal of Pharmaceutical Sciences , 97 6 , — International Journal of Pharmaceutical and Chemical Sciences , 1 1 , Development of novel flurbiprofen-loaded solid self-microemulsifying drug delivery system using gelatin as solid carrier. Journal of Microencapsulation , 29 4 , — Pharmaceutical Nanotechnology , 6, Hydrotropic polymeric micelles for enhanced paclitaxel solubility: In vitro and in vivo characterization.


Biomacromolecules , 8 1 , — Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles. Journal of Controlled Release , 3 , — Nanoscale Research Letters , 12, Solubilization by cosolvents. International Journal of Pharmaceutics , 1 , — Hot-melt extrusion for enhanced delivery of drug particles. Journal of Pharmaceutical Sciences , 96 2 , — Pharmaceutical co-crystals — an opportunity for drug product enhancement. Expert Opinion on Drug Delivery , 6 4 , — Pharmaceutical Research , 11 2 , European Journal of Pharmaceutics and Biopharmaceutics , 50 1 , European Journal of Pharmaceutical Sciences , 13 2 , — Enhancement of dissolution rate and bioavailability of aceclofenac: A chitosan-based solvent change approach.

Hydrotropy: A promising tool for solubility Enhancement: A Review. International Journal of Drug Development and Research, 3 2 , International Journal of Pharmacy and Biological Sciences , 2 2 , Formation of itraconazole—succinic acid cocrystals by gas antisolvent cocrystallization. PEGylated nanoparticles for biological and pharmaceutical applications.

Advanced Drug Delivery Reviews , 55 3 , — Design and development of a self-nanoemulsifying drug delivery system for telmisartan for oral drug delivery.